Cytarabine [cytarabin]
- Terms
-
Alexan
arabinofuranosylcytosin
arabinosylcytosin
aracytidin
cytarabin hydrochlorid
Cytarabine Accord
Cytosar
cytosinarabinosid
Vyxeos liposomal
-
Ara-C
Arabinofuranosylcytosine
Arabinosylcytosine
Aracytidine
Aracytine
beta-Ara C
Cytarabine Hydrochloride
Cytonal
Cytosar
Cytosar-U
Cytosine Arabinoside
A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
- DUI
- D003561 MeSH Browser
- CUI
- M0005564
- CAS
- 2(1H)-Pyrimidinone, 4-amino-1-beta-D-arabinofuranosyl-
- History note
- 1966
- Public note
- 1966
Allowable subheadings
- AD
- administration & dosage 59
- AE
- adverse effects 17
- AG
- agonists 0
- AA
- analogs & derivatives 8
- AN
- analysis 1
- AI
- antagonists & inhibitors 2
- BL
- blood 2
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 1
- CH
- chemistry 0
- CL
- classification 0
- EC
- economics 0
- HI
- history 1
- IM
- immunology 0
- IP
- isolation & purification 1
- ME
- metabolism 5
- PK
- pharmacokinetics 5
- PD
- pharmacology 25
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 57
- TO
- toxicity 4
- UR
- urine 0