A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)

Annotation

coordinate with probably OVARIAN NEOPLASMS

DUI

D004407 MeSH Browser

CUI

M0006918

History note

79; was DISGERMINOMA 1963-78

Online note

use DYSGERMINOMA to search DISGERMINOMA 1966-78

Public note

79; was DISGERMINOMA 1963-78