A fulminant and often fatal demyelinating disease of the brain which primarily affects young adults and children. Clinical features include the rapid onset of weakness, SEIZURES, and COMA. It may follow a viral illness or MYCOPLASMA PNEUMONIAE infections but in most instances there is no precipitating event. Pathologic examination reveals marked perivascular demyelination and necrosis of white matter with microhemorrhages. (Adams et al., Principles of Neurology, 6th ed, pp924-5)

DUI

D004684 MeSH Browser

CUI

M0007374

Previous indexing

Demyelinating Diseases (1966-1971); Encephalomyelitis (1966-1971)

History note

1997; was ENCEPHALOMYELITIS, NECROTIZING HEMORRHAGIC 1991-1996 (see under ENCEPHALOMYELITIS 1972-1990); HURST DISEASE was HURST'S DISEASE 1997

Public note

1997; was ENCEPHALOMYELITIS, NECROTIZING HEMORRHAGIC 1991-1996 (see under ENCEPHALOMYELITIS 1972-1990); HURST DISEASE was HURST'S DISEASE 1997