An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Annotation

an antiviral & antineoplastic antimetabolite

DUI

D005467 MeSH Browser

CUI

M0008626

CAS

Uridine, 2'-deoxy-5-fluoro-

History note

93; was FLUORODEOXYURIDINE 1963-92; FLOXURIDINE was see FLUORODEOXYURIDINE 1976-92

Online note

use FLOXURIDINE to search FLUORODEOXYURIDINE 1966-92

Public note

93; was FLUORODEOXYURIDINE 1963-92; FLOXURIDINE was see FLUORODEOXYURIDINE 1976-92