GTP Cyclohydrolase [GTP-cyklohydrolasa]
- Terms
-
GTP-cyklohydrolasa I
GTP-cyklohydrolasa II
GTP-cyklohydroláza
GTP-cyklohydroláza I
GTP-cyklohydroláza II
GTP-dihydroláza
-
7,8-Dihydroneopterintriphosphate Synthetase
GTP 8-Formylhydrolase
GTP Cyclohydrolase I
GTP Cyclohydrolase II
GTP Dihydrolase
GTP Ring-Opening Enzyme
(GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II).
- DUI
- D006136 MeSH Browser
- CUI
- M0009663
- CAS
- GTP 7,8-8,9-dihydrolase
- Previous indexing
- Aminohydrolases (1974); Guanosine Triphosphate (1974)
- History note
- 91(75); was see under AMINOHYDROLASES 1975-90
- Public note
- 91; was see under AMINOHYDROLASES 1975-90
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
GCH1 protein, human Chemical MeSH Browser
Gch1 protein, mouse Chemical MeSH Browser
Gch1 protein, rat Chemical MeSH Browser
RibBA protein, Helicobacter pylori Chemical MeSH Browser
erythro-dihydrobiopterin triphosphate synthetase Chemical MeSH Browser