Cyklický guaninový nukleotid obsahující jednu fosfátovou skupinu, která je připojena esterovou vazbou na ribózu v polohách 3'- a 5'-. Podílí se na buněčné regulaci, patří mezi tzv. druhé posly. Jeho hladiny se zvyšují v reakci na různé hormony včetně acetylcholinu, inzulinu a oxytocinu. Bylo zjištěno, že aktivuje specifické proteinkinázy.

Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)

DUI

D006152 MeSH Prohlížeč

CUI

M0009685

CAS

Guanosine, cyclic 3',5'-(hydrogen phosphate)

Předchozí užití

Guanine Nucleotides (1966-1971)

Historická pozn.

94; was GUANOSINE CYCLIC MONOPHOSPHATE 1980-93, was GUANOSINE CYCLIC-3',5'-MONOPHOSPHATE 1978-79, was GUANOSINE CYCLIC 3',5' MONOPHOSPHATE 1971-77 (Prov 1971); CYCLIC GMP was see GUANOSINE CYCLIC MONOPHOSPHATE 1975-93; GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE was see GUANOSINE CYCLIC MONOPHOSPHATE 1980-93

Online pozn.

use CYCLIC GMP to search GUANOSINE CYCLIC MONOPHOSPHATE & GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE 1980-93 & GUANOSINE CYCLIC-3',5'-MONOPHOSPHATE 1971-79 (as Prov 1971)

Veřejná pozn.

94; was GUANOSINE CYCLIC MONOPHOSPHATE 1980-93, was GUANOSINE CYCLIC-3',5'-MONOPHOSPHATE 1978-79, was GUANOSINE CYCLIC 3',5' MONOPHOSPHATE 1972-77; CYCLIC GMP was see GUANOSINE CYCLIC MONOPHOSPHATE 1975-93; GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE was see GUANOSINE CYCLIC MONOPHOSPHATE 1980-93