Histone Deacetylases [histondeacetylasy]
topical
69
- Terms
-
histondeacetylasa
histondeacetylasové komplexy
histondeacetylasy třídy I
histondeacetylasy třídy II
histondeacetyláza
histondeacetylázové komplexy
histondeacetylázy
histondeacetylázy třídy I
histondeacetylázy třídy II
-
Class I Histone Deacetylases
Class II Histone Deacetylases
HDAC Proteins
Histone Deacetylase
Histone Deacetylase Complexes
Persistent link
https://www.medvik.cz/link/D006655
Definition
Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.
- DUI
- D006655 MeSH Browser
- CUI
- M0010420
- Previous indexing
- Acetic Acids (1971-1974); Amidohydrolases (1971-1974); Histones (1971-1974)
- History note
- 2003; use AMIDOHYDROLASES 1975-1990
- Public note
- 2003; see HISTONE DEACETYLASE 1991-2002; see AMIDOHYDROLASES 1975-1990
Combination
- antagonists & inhibitors
- Histone Deacetylase Inhibitors
Allowable subheadings
- AD
- administration & dosage 4
- AE
- adverse effects 0
- AN
- analysis 2
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 3
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 5
- EC
- economics 0
- GE
- genetics 20
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 28
- PK
- pharmacokinetics 1
- PD
- pharmacology 4
- PH
- physiology 4
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 11
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.277.087.060
Allophanate Hydrolase
D08.811.277.087.100
Arylformamidase
D08.811.277.087.125
Aspartylglucosylaminase
D08.811.277.087.200
Biotinidase
D08.811.277.087.250
Ceramidases
D08.811.277.087.280
Dihydroorotase
D08.811.277.087.520.200
Group III Histone Deacetylases
D08.811.277.087.520.750
Sin3 Histone Deacetylase and Corepressor Complex
D08.811.277.087.760
Pyroglutamate Hydrolase