The domains of the immunoglobulin molecules that are invariable in their amino acid sequence within any class or subclass of immunoglobulin. They confer biological as well as structural functions to immunoglobulins. One each on both the light chains and the heavy chains comprises the C-terminus half of the IMMUNOGLOBULIN FAB FRAGMENT and two or three of them make up the rest of the heavy chains (all of the IMMUNOGLOBULIN FC FRAGMENT)

DUI

D007127 MeSH Browser

CUI

M0011105

Previous indexing

Gamma Globulins (1966-1971); Immunoglobulin Allotypes (1975-1978); Immunoglobulins (1972-1978); Immunoglobulins, Fc (1973); specific immunoglobulin fragment (1973-1978)

History note

2006 (1979)

Online note

use IMMUNOGLOBULIN CONSTANT REGION to search CONSTANT REGION, IG 1979-91

Public note

2006; see IMMUNOGLOBULIN CONSTANT REGION 1988-2005, see IMMUNOGLOBULINS 1979-1987; for CONSTANT REGION IG see IMMUNOGLOBULIN CONSTANT REGION 1979-1991