Immunoglobulin Joining Region [imunoglobuliny - vazebný region]

topical
2
Terms

Immunoglobulin Joining Region Peptide Fragments
Joining Region, Ig

Persistent link   https://www.medvik.cz/link/D007133
Definition

A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.

DUI
D007133 MeSH Browser
CUI
M0011112
Previous indexing
Amino Acid Sequence (1971-1987); Immunoglobulin Constant Region (1979-1987); Immunoglobulins, Heavy Chain (1977-1987); Immunoglobulin Variable Region (1977-1987)
History note
88
Public note
88

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis 1
BI
biosynthesis 1
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics 2
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 383
D12.644.541 Peptide Fragments 362
D12.644.541.500 Immunoglobulin Fragments 187
D12.644.541.500.650 Immunoglobulin Fab Fragments 65
D12.644.541.500.650.500 Immunoglobulin Variable Region 36
D12.644.541.500.650.500.180 Complementarity Determining Regions 16
D12.644.541.500.650.500.590 Immunoglobulin Joining Region 2
D12.644.541.500.650.500.800 Single-Chain Antibodies 8
D12.644.541.500.650.500.900 Single-Domain Antibodies 7
D12.776 Proteins 2 581
D12.776.124 Blood Proteins 909
D12.776.124.486 Immunoproteins 14
D12.776.124.486.485 Immunoglobulins 1 492
D12.776.124.486.485.680 Immunoglobulin Fragments 187
D12.776.124.486.485.680.650 Immunoglobulin Fab Fragments 65
D12.776.124.486.485.680.650.500 Immunoglobulin Variable Region 36
D12.776.124.486.485.680.650.500.180 Complementarity Determining Regions 16
D12.776.124.486.485.680.650.500.590 Immunoglobulin Joining Region 2
D12.776.124.486.485.680.650.500.800 Single-Chain Antibodies 8
D12.776.124.486.485.680.650.500.900 Single-Domain Antibodies 7
D12.776.124.486.485.797 Immunoglobulin Variable Region 36
D12.776.124.486.485.797.180 Complementarity Determining Regions 16
D12.776.124.486.485.797.590 Immunoglobulin Joining Region 2
D12.776.124.790 Serum Globulins 61
D12.776.124.790.651 Immunoglobulins 1 492
D12.776.124.790.651.680 Immunoglobulin Fragments 187
D12.776.124.790.651.680.650 Immunoglobulin Fab Fragments 65
D12.776.124.790.651.680.650.500 Immunoglobulin Variable Region 36
D12.776.124.790.651.680.650.500.180 Complementarity Determining Regions 16
D12.776.124.790.651.680.650.500.590 Immunoglobulin Joining Region 2
D12.776.124.790.651.680.650.500.800 Single-Chain Antibodies 8
D12.776.124.790.651.680.650.500.900 Single-Domain Antibodies 7
D12.776.124.790.651.797 Immunoglobulin Variable Region 36
D12.776.124.790.651.797.180 Complementarity Determining Regions 16
D12.776.124.790.651.797.590 Immunoglobulin Joining Region 2
D12.776.377 Globulins 68
D12.776.377.715 Serum Globulins 61
D12.776.377.715.548 Immunoglobulins 1 492
D12.776.377.715.548.680 Immunoglobulin Fragments 187
D12.776.377.715.548.680.650 Immunoglobulin Fab Fragments 65
D12.776.377.715.548.680.650.500 Immunoglobulin Variable Region 36
D12.776.377.715.548.680.650.500.180 Complementarity Determining Regions 16
D12.776.377.715.548.680.650.500.590 Immunoglobulin Joining Region 2
D12.776.377.715.548.680.650.500.795 Single-Chain Antibodies 8
D12.776.377.715.548.680.650.500.897 Single-Domain Antibodies 7
D12.776.377.715.548.797 Immunoglobulin Variable Region 36
D12.776.377.715.548.797.180 Complementarity Determining Regions 16
D12.776.377.715.548.797.590 Immunoglobulin Joining Region 2

Add