Immunoglobulin Fab Fragments [imunoglobuliny - Fab fragmenty]

topical
65
Terms

Fab fragmenty
imunoglobuliny Fab

 

Fab Fragment
Fab Fragments
Fab Immunoglobulin Fragments
Ig Fab Fragments
Immunoglobulin Fab Fragment
Immunoglobulins, Fab
Immunoglobulins, Fab Fragment

Persistent link   https://www.medvik.cz/link/D007140
Definition

Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

DUI
D007140 MeSH Browser
CUI
M0011126
Previous indexing
Immunoglobulins (1970-1972)
History note
2006 (1973)
Public note
2006; was IMMUNOGLOBULINS, FAB 1973-2005

Allowable subheadings

AD
administration & dosage 28
AE
adverse effects 10
AN
analysis
BI
biosynthesis 1
BL
blood
CF
cerebrospinal fluid
CH
chemistry 11
CL
classification 1
DE
drug effects
EC
economics
GE
genetics 1
HI
history
IM
immunology 4
IP
isolation & purification 1
ME
metabolism 4
PD
pharmacology 15
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use 33
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 382
D12.644.541 Peptide Fragments 358
D12.644.541.500 Immunoglobulin Fragments 187
D12.644.541.500.650 Immunoglobulin Fab Fragments 65
D12.644.541.500.650.125 Abciximab 14
D12.644.541.500.650.250 Certolizumab Pegol 47
D12.644.541.500.650.500 Immunoglobulin Variable Region 36
D12.644.541.500.650.750 Tuftsin 5
D12.644.541.500.697 Immunoglobulin Fc Fragments 48
D12.644.541.500.745 Immunoglobulin Idiotypes 10
D12.776 Proteins 2 577
D12.776.124 Blood Proteins 909
D12.776.124.486 Immunoproteins 14
D12.776.124.486.485 Immunoglobulins 1 489
D12.776.124.486.485.680 Immunoglobulin Fragments 187
D12.776.124.486.485.680.650 Immunoglobulin Fab Fragments 65
D12.776.124.486.485.680.650.125 Abciximab 14
D12.776.124.486.485.680.650.250 Certolizumab Pegol 47
D12.776.124.486.485.680.650.500 Immunoglobulin Variable Region 36
D12.776.124.486.485.680.650.750 Tuftsin 5
D12.776.124.486.485.680.697 Immunoglobulin Fc Fragments 48
D12.776.124.486.485.680.745 Immunoglobulin Idiotypes 10
D12.776.124.790 Serum Globulins 61
D12.776.124.790.651 Immunoglobulins 1 489
D12.776.124.790.651.680 Immunoglobulin Fragments 187
D12.776.124.790.651.680.650 Immunoglobulin Fab Fragments 65
D12.776.124.790.651.680.650.125 Abciximab 14
D12.776.124.790.651.680.650.250 Certolizumab Pegol 47
D12.776.124.790.651.680.650.500 Immunoglobulin Variable Region 36
D12.776.124.790.651.680.650.750 Tuftsin 5
D12.776.124.790.651.680.660 Immunoglobulin Fc Fragments 48
D12.776.124.790.651.680.745 Immunoglobulin Idiotypes 10
D12.776.377 Globulins 68
D12.776.377.715 Serum Globulins 61
D12.776.377.715.548 Immunoglobulins 1 489
D12.776.377.715.548.680 Immunoglobulin Fragments 187
D12.776.377.715.548.680.650 Immunoglobulin Fab Fragments 65
D12.776.377.715.548.680.650.125 Abciximab 14
D12.776.377.715.548.680.650.250 Certolizumab Pegol 47
D12.776.377.715.548.680.650.500 Immunoglobulin Variable Region 36
D12.776.377.715.548.680.650.750 Tuftsin 5
D12.776.377.715.548.680.660 Immunoglobulin Fc Fragments 48
D12.776.377.715.548.680.745 Immunoglobulin Idiotypes 10

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