Abciximab [abciximab]

topical
14
Terms

Reopro
ReoPro

 

c7E3 Fab
CentoRx
Chimeric 7E3 Fab
Clotinab
ReoPro

Persistent link   https://www.medvik.cz/link/D000077284
Definition

A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.

DUI
D000077284 MeSH Browser
CUI
M0227707
History note
2019 (1994)
Public note
2019; ABCIXIMAB was indexed under ANTIBODIES, MONOCLONAL and IMMUNOGLOBULIN FAB FRAGMENTS 1994-2018

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 389
D12.644.541 Peptide Fragments 369
D12.644.541.500 Immunoglobulin Fragments 187
D12.644.541.500.650 Immunoglobulin Fab Fragments 65
D12.644.541.500.650.125 Abciximab 14
D12.644.541.500.650.250 Certolizumab Pegol 48
D12.644.541.500.650.500 Immunoglobulin Variable Region 36
D12.644.541.500.650.750 Tuftsin 5
D12.776 Proteins 2 584
D12.776.124 Blood Proteins 910
D12.776.124.486 Immunoproteins 14
D12.776.124.486.485 Immunoglobulins 1 493
D12.776.124.486.485.114 Antibodies 1 816
D12.776.124.486.485.114.224 Antibodies, Monoclonal 4 693
D12.776.124.486.485.114.224.060 Antibodies, Monoclonal, Humanized 2 935
D12.776.124.486.485.114.224.060.125 Abciximab 14
D12.776.124.486.485.114.224.060.250 Adalimumab 353
D12.776.124.486.485.114.224.060.313 Alemtuzumab 125
D12.776.124.486.485.114.224.060.344 Basiliximab 2
D12.776.124.486.485.114.224.060.375 Bevacizumab 453
D12.776.124.486.485.114.224.060.438 Brentuximab Vedotin 44
D12.776.124.486.485.114.224.060.500 Certolizumab Pegol 48
D12.776.124.486.485.114.224.060.750 Cetuximab 186
D12.776.124.486.485.114.224.060.766 Daclizumab 6
D12.776.124.486.485.114.224.060.782 Denosumab 157
D12.776.124.486.485.114.224.060.790 Gemtuzumab 18
D12.776.124.486.485.114.224.060.794 Inotuzumab Ozogamicin 12
D12.776.124.486.485.114.224.060.798 Ipilimumab 267
D12.776.124.486.485.114.224.060.813 Natalizumab 158
D12.776.124.486.485.114.224.060.829 Nivolumab 459
D12.776.124.486.485.114.224.060.844 Omalizumab 114
D12.776.124.486.485.114.224.060.860 Palivizumab 13
D12.776.124.486.485.114.224.060.864 Panitumumab 62
D12.776.124.486.485.114.224.060.866 Ramucirumab 1
D12.776.124.486.485.114.224.060.868 Ranibizumab 63
D12.776.124.486.485.114.224.060.875 Trastuzumab 278
D12.776.124.486.485.114.224.060.937 Ustekinumab 124
D12.776.124.486.485.680 Immunoglobulin Fragments 187
D12.776.124.486.485.680.650 Immunoglobulin Fab Fragments 65
D12.776.124.486.485.680.650.125 Abciximab 14
D12.776.124.486.485.680.650.250 Certolizumab Pegol 48
D12.776.124.486.485.680.650.500 Immunoglobulin Variable Region 36
D12.776.124.486.485.680.650.750 Tuftsin 5
D12.776.124.790 Serum Globulins 61
D12.776.124.790.651 Immunoglobulins 1 493
D12.776.124.790.651.114 Antibodies 1 816
D12.776.124.790.651.114.224 Antibodies, Monoclonal 4 693
D12.776.124.790.651.114.224.060 Antibodies, Monoclonal, Humanized 2 935
D12.776.124.790.651.114.224.060.125 Abciximab 14
D12.776.124.790.651.114.224.060.250 Adalimumab 353
D12.776.124.790.651.114.224.060.375 Alemtuzumab 125
D12.776.124.790.651.114.224.060.407 Basiliximab 2
D12.776.124.790.651.114.224.060.438 Bevacizumab 453
D12.776.124.790.651.114.224.060.469 Brentuximab Vedotin 44
D12.776.124.790.651.114.224.060.500 Certolizumab Pegol 48
D12.776.124.790.651.114.224.060.750 Cetuximab 186
D12.776.124.790.651.114.224.060.766 Daclizumab 6
D12.776.124.790.651.114.224.060.782 Denosumab 157
D12.776.124.790.651.114.224.060.790 Gemtuzumab 18
D12.776.124.790.651.114.224.060.794 Inotuzumab Ozogamicin 12
D12.776.124.790.651.114.224.060.798 Ipilimumab 267
D12.776.124.790.651.114.224.060.813 Natalizumab 158
D12.776.124.790.651.114.224.060.829 Nivolumab 459
D12.776.124.790.651.114.224.060.844 Omalizumab 114
D12.776.124.790.651.114.224.060.860 Palivizumab 13
D12.776.124.790.651.114.224.060.864 Panitumumab 62
D12.776.124.790.651.114.224.060.866 Ramucirumab 1
D12.776.124.790.651.114.224.060.868 Ranibizumab 63
D12.776.124.790.651.114.224.060.875 Trastuzumab 278
D12.776.124.790.651.114.224.060.937 Ustekinumab 124
D12.776.124.790.651.680 Immunoglobulin Fragments 187
D12.776.124.790.651.680.650 Immunoglobulin Fab Fragments 65
D12.776.124.790.651.680.650.125 Abciximab 14
D12.776.124.790.651.680.650.250 Certolizumab Pegol 48
D12.776.124.790.651.680.650.500 Immunoglobulin Variable Region 36
D12.776.124.790.651.680.650.750 Tuftsin 5
D12.776.377 Globulins 68
D12.776.377.715 Serum Globulins 61
D12.776.377.715.548 Immunoglobulins 1 493
D12.776.377.715.548.114 Antibodies 1 816
D12.776.377.715.548.114.224 Antibodies, Monoclonal 4 693
D12.776.377.715.548.114.224.200 Antibodies, Monoclonal, Humanized 2 935
D12.776.377.715.548.114.224.200.125 Abciximab 14
D12.776.377.715.548.114.224.200.250 Adalimumab 353
D12.776.377.715.548.114.224.200.375 Alemtuzumab 125
D12.776.377.715.548.114.224.200.407 Basiliximab 2
D12.776.377.715.548.114.224.200.438 Bevacizumab 453
D12.776.377.715.548.114.224.200.469 Brentuximab Vedotin 44
D12.776.377.715.548.114.224.200.500 Certolizumab Pegol 48
D12.776.377.715.548.114.224.200.750 Cetuximab 186
D12.776.377.715.548.114.224.200.766 Daclizumab 6
D12.776.377.715.548.114.224.200.782 Denosumab 157
D12.776.377.715.548.114.224.200.790 Gemtuzumab 18
D12.776.377.715.548.114.224.200.794 Inotuzumab Ozogamicin 12
D12.776.377.715.548.114.224.200.798 Ipilimumab 267
D12.776.377.715.548.114.224.200.813 Natalizumab 158
D12.776.377.715.548.114.224.200.829 Nivolumab 459
D12.776.377.715.548.114.224.200.844 Omalizumab 114
D12.776.377.715.548.114.224.200.860 Palivizumab 13
D12.776.377.715.548.114.224.200.864 Panitumumab 62
D12.776.377.715.548.114.224.200.866 Ramucirumab 1
D12.776.377.715.548.114.224.200.868 Ranibizumab 63
D12.776.377.715.548.114.224.200.875 Trastuzumab 278
D12.776.377.715.548.114.224.200.937 Ustekinumab 124
D12.776.377.715.548.680 Immunoglobulin Fragments 187
D12.776.377.715.548.680.650 Immunoglobulin Fab Fragments 65
D12.776.377.715.548.680.650.125 Abciximab 14
D12.776.377.715.548.680.650.250 Certolizumab Pegol 48
D12.776.377.715.548.680.650.500 Immunoglobulin Variable Region 36
D12.776.377.715.548.680.650.750 Tuftsin 5

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