Abciximab [abciximab]
topical
14
- Terms
-
Reopro
ReoPro
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c7E3 Fab
CentoRx
Chimeric 7E3 Fab
Clotinab
ReoPro
Persistent link
https://www.medvik.cz/link/D000077284
Definition
A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.
- DUI
- D000077284 MeSH Browser
- CUI
- M0227707
- History note
- 2019 (1994)
- Public note
- 2019; ABCIXIMAB was indexed under ANTIBODIES, MONOCLONAL and IMMUNOGLOBULIN FAB FRAGMENTS 1994-2018
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CH
- chemistry 0
- CL
- classification 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- TU
- therapeutic use 0
- TO
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- ultrastructure 0
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- urine 0
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Occurrences in Medvik records
D
Chemicals and Drugs