Immunoglobulin Fab Fragments [imunoglobuliny - Fab fragmenty]
topical
65
- Terms
-
Fab fragmenty
imunoglobuliny Fab
-
Fab Fragment
Fab Fragments
Fab Immunoglobulin Fragments
Ig Fab Fragments
Immunoglobulin Fab Fragment
Immunoglobulins, Fab
Immunoglobulins, Fab Fragment
Persistent link
https://www.medvik.cz/link/D007140
Definition
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
- DUI
- D007140 MeSH Browser
- CUI
- M0011126
- Previous indexing
- Immunoglobulins (1970-1972)
- History note
- 2006 (1973)
- Public note
- 2006; was IMMUNOGLOBULINS, FAB 1973-2005
Allowable subheadings
- AD
- administration & dosage 28
- AE
- adverse effects 10
- AN
- analysis 0
- BI
- biosynthesis 1
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CH
- chemistry 11
- CL
- classification 1
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 1
- HI
- history 0
- IM
- immunology 4
- IP
- isolation & purification 1
- ME
- metabolism 4
- PD
- pharmacology 15
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- TU
- therapeutic use 33
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs