Immunologic Capping [imunologický capping]

topical
1
Terms

Capping, Immunologic
Immunological Capping

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Definition

An energy dependent process following the crosslinking of B CELL ANTIGEN RECEPTORS by multivalent ligands (bivalent anti-antibodies, LECTINS or ANTIGENS), on the B-cell surface. The crosslinked ligand-antigen receptor complexes collect in patches which flow to and aggregate at one pole of the cell to form a large mass - the cap. The caps may then be endocytosed or shed into the environment.

Annotation
may appear in the literature as "capping of lymphocytes" or "leukocyte capping"; do not confuse with RECEPTOR CAPPING
DUI
D007152 MeSH Browser
CUI
M0011153
Previous indexing
Cell Membrane (1966-1977); Lymphocytes (1966-1977)
History note
78
Public note
78