A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.

DUI

D007335 MeSH Browser

CUI

M0011435

CAS

Insulin-like growth factor II

Previous indexing

Growth Substances (1966-1985); Insulin (1966-1985); Peptides (1966-1985); Somatomedins (1973-1985); Sulfation Factor (1971-1972); Blood Proteins (1966-1985)

History note

1991(1986)

Public note

1991; see SOMATOMEDINS 1986-1990; SOMATOMEDIN A was indexed under INSULIN-LIKE GROWTH FACTOR II 1980-2004