Interferon-gamma [interferon gama]
- Terms
-
interferon typ II
-
gamma-Interferon
Interferon Type II
Interferon, gamma
Interferon, Immune
Type II Interferon
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
- DUI
- D007371 MeSH Browser
- CUI
- M0011490
- CAS
- Interferon gamma (human lymphocyte protein moiety reduced)
- Previous indexing
- Interferons (1966-1982)
- History note
- 2009(1983); INTERFERON-GAMMA was INTERFERON, GAMMA 1983-1990
- Public note
- 2009; see INTERFERON TYPE II 1984-2008, see INTERFERON, GAMMA 1983-1990
Allowable subheadings
- AD
- administration & dosage 12
- AE
- adverse effects 4
- AG
- agonists 1
- AN
- analysis 9
- AI
- antagonists & inhibitors 2
- BI
- biosynthesis 35
- BL
- blood 38
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 5
- CL
- classification
- DF
- deficiency 2
- DE
- drug effects 8
- EC
- economics
- GE
- genetics 34
- HI
- history
- IM
- immunology 48
- IP
- isolation & purification 4
- ME
- metabolism 53
- PK
- pharmacokinetics 4
- PD
- pharmacology 43
- PH
- physiology 11
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 33
- TO
- toxicity 1
- UL
- ultrastructure
- UR
- urine
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