An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.

Annotation

/defic: consider also HYPERLIPOPROTEINEMIA TYPE I

/nedostatek: zvaž také deskriptor HYPERLIPOPROTEINEMIE TYP I

DUI

D008071 MeSH Browser

CUI

M0012578

CAS

Triacylglycero-protein acylhydrolase

History note

HEPARIN-CLEARING FACTOR & LIPEMIA-CLEARING FACTOR were see under LIPOPROTEIN LIPASE 1963-80

Online note

use LIPOPROTEIN LIPASE to search HEPARIN-CLEARING FACTOR & LIPEMIA-CLEARING FACTOR 1966-80