Methylmalonyl-CoA Mutase [methylmalonyl-CoA-mutasa]
topical
4
- Terms
-
methylmalonyl-CoA-mutáza
metylmalonyl-CoA-mutáza
-
Methylmalonyl-CoA Isomerase
Persistent link
https://www.medvik.cz/link/D008765
Definition
An enzyme that catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA by transfer of the carbonyl group. It requires a cobamide coenzyme. A block in this enzymatic conversion leads to the metabolic disease, methylmalonic aciduria. EC 5.4.99.2.
- Annotation
- /defic: consider also METHYLMALONIC ACID /urine (IM) + AMINO ACID METABOLISM, INBORN ERRORS (IM)
- DUI
- D008765 MeSH Browser
- CUI
- M0013647
- CAS
- (R)-2-Methyl-3-oxopropanoyl-CoA CoA-carbonylmutase
- Previous indexing
- Isomerases (1969-1974); Malonates (1969-1974)
- History note
- 91(75); was see under ISOMERASES 1975-90
- Public note
- 91; was see under ISOMERASES 1975-90
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects 1
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency 1
- DE
- drug effects 1
- EC
- economics
- GE
- genetics 3
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 3
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.399.520.100
2-Acetolactate Mutase
D08.811.399.520.250
Chorismate Mutase