Mitotane [mitotan]
topical
13
- Terms
-
Lysodren
-
Chloditan
Chlodithane
Khloditan
Lysodren
Mytotan
o,p-DDD
ortho,para-DDD
Persistent link
https://www.medvik.cz/link/D008939
Definition
A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
- DUI
- D008939 MeSH Browser
- CUI
- M0013951
- CAS
- Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-
- Previous indexing
- DDD/PD (1966-1972)
- History note
- 73
- Public note
- 73
Allowable subheadings
- AD
- administration & dosage 4
- AE
- adverse effects 4
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology 2
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 11
- TO
- toxicity 1
- UR
- urine
...
Occurrences in Medvik records