Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents.

DUI

D009150 MeSH Prohlížeč

CUI

M0014270

Historická pozn.

68

Veřejná pozn.

68; MUSTARD GAS was heading 1963-67