Neurotensin [neurotensin]
A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hypotension in the rat, to stimulate contraction of guinea pig ileum and rat uterus, and to cause relaxation of rat duodenum. There is also evidence that it acts as both a peripheral and a central nervous system neurotransmitter.
- Annotation
- a neurotransmitter isolated from the hypothalamus; /biosyn /physiol permitted
- DUI
- D009496 MeSH Browser
- CUI
- M0014773
- CAS
- Neurotensin
- Previous indexing
- Peptides (1966-1977); Kinins (1966-1977); Nerve Tissue Proteins (1966-1977)
- History note
- 78
- Public note
- 78
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects
- AG
- agonists 1
- AA
- analogs & derivatives 1
- AN
- analysis 1
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 4
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PH
- physiology 3
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UR
- urine
(VIP-neurotensin) hybrid antagonist Chemical MeSH Browser
neuromedin N Chemical MeSH Browser
neuromedin N precursor Chemical MeSH Browser
neurotensin (1-10) Chemical MeSH Browser
neurotensin (1-11) Chemical MeSH Browser
neurotensin (1-8) Chemical MeSH Browser
neurotensin (8-13) Chemical MeSH Browser
neurotensin (9-13) Chemical MeSH Browser
proneurotensin Chemical MeSH Browser
stearyl-Nle(17)-neurotensin(6-11)VIP(7-28) Chemical MeSH Browser
tumor-specific tetrabranched peptide NT4 Chemical MeSH Browser
vasoactive intestinal peptide-neurotensin hybrid Chemical MeSH Browser
xenin 25 Chemical MeSH Browser