Fenclonine [fenklonin]
- Terms
-
p-chlorfenylalanin
-
CP-10,188
DL-3-(4-Chlorophenyl)alanine
Fenclonin
Fenclonine (L)-Isomer
Fenclonine Hydrobromide
Fenclonine Hydrochloride
Fenclonine, (D)-Isomer
p-Chlorophenylalanine
para-Chlorophenylalanine
A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
- DUI
- D010134 MeSH Browser
- CUI
- M0015725
- CAS
- DL-Phenylalanine, 4-chloro-
- Previous indexing
- Phenylalanine (1966-1970)
- History note
- 93(71)
- Public note
- 93; see P-CHLOROPHENYLALANINE 1973-92; for FENCLONINE see P-CHLOROPHENYLALANINE 1978-92
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives 1
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 2
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 2
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine