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Pactamycin [paktamycin]

topical
Persistent link   https://www.medvik.cz/link/D010142
Definition

Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.

DUI
D010142 MeSH Browser
CUI
M0015738
CAS
Benzoic acid, 2-hydroxy-6-methyl-, (5-((3-acetylphenyl)amino)-4-amino-3-(((dimethylamino)carbonyl)amino)-1,2-dihydroxy-3-(1-hydroxyethyl)-2-methylcyclopentyl)methyl ester, (1S-(1alpha,2beta,3alpha,3(R*),4alpha,5beta))-
Previous indexing
Antibiotics, Antineoplastic (1972-1974)
History note
91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
Public note
91; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine

D Chemicals and Drugs
D02 Organic Chemicals 391
D02.241 Carboxylic Acids 244
D02.241.223 Acids, Carbocyclic 4
D02.241.223.100 Benzoates 214
D02.241.223.100.300 Hydroxybenzoates 57
D02.241.223.100.300.100 Depsides 8
D02.241.223.100.300.200 Gallic Acid 23
D02.241.223.100.300.300 3-Hydroxyanthranilic Acid 1
D02.241.223.100.300.350 Hydroxybenzoate Ethers
D02.241.223.100.300.400 Hydroxymercuribenzoates
D02.241.223.100.300.450 Pactamycin
D02.241.223.100.300.460 Parabens 43
D02.241.223.100.300.595 Salicylates 300
D02.241.511 Hydroxy Acids 24
D02.241.511.390 Hydroxybenzoates 57
D02.241.511.390.100 Depsides 8
D02.241.511.390.200 Gallic Acid 23
D02.241.511.390.300 3-Hydroxyanthranilic Acid 1
D02.241.511.390.350 Hydroxybenzoate Ethers
D02.241.511.390.400 Hydroxymercuribenzoates
D02.241.511.390.450 Pactamycin
D02.241.511.390.460 Parabens 43
D02.241.511.390.595 Salicylates 300
D02.455 Hydrocarbons 139
D02.455.426 Hydrocarbons, Cyclic 24
D02.455.426.559 Hydrocarbons, Aromatic 50
D02.455.426.559.389 Benzene Derivatives 73
D02.455.426.559.389.127 Benzoates 214
D02.455.426.559.389.127.281 Hydroxybenzoates 57
D02.455.426.559.389.127.281.100 Depsides 8
D02.455.426.559.389.127.281.200 Gallic Acid 23
D02.455.426.559.389.127.281.350 Hydroxybenzoate Ethers
D02.455.426.559.389.127.281.400 Hydroxymercuribenzoates
D02.455.426.559.389.127.281.450 Pactamycin
D02.455.426.559.389.127.281.460 Parabens 43
D02.455.426.559.389.127.281.595 Salicylates 300
D02.455.426.559.389.657 Phenols 689
D02.455.426.559.389.657.410 Hydroxybenzoates 57
D02.455.426.559.389.657.410.100 Depsides 8
D02.455.426.559.389.657.410.200 Gallic Acid 23
D02.455.426.559.389.657.410.400 Hydroxymercuribenzoates
D02.455.426.559.389.657.410.450 Pactamycin
D02.455.426.559.389.657.410.460 Parabens 43
D02.455.426.559.389.657.410.595 Salicylates 300

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