Podophyllotoxin [podofylotoxin]

topical
18
Terms

Condyline
Condylox
CPH86
Epipodophyllotoxin
Podocon-25
Podofilm
Podofilox
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer
Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer
Wartec
Warticon

Persistent link   https://www.medvik.cz/link/D011034
Definition

A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.

Annotation
/biosyn permitted if by plant
DUI
D011034 MeSH Browser
CUI
M0017087
CAS
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-
Previous indexing
Alkaloids (1966-1972); Antineoplastic Agents (1966-1972)
History note
73; EPIPODOPHYLLOTOXIN was see under PODOPHYLLOTOXIN 1975
Online note
use PODOPHYLLOTOXIN to search EPIPODOPHYLLOTOXIN 1975
Public note
73; EPIPODOPHYLLOTOXIN was see under PODOPHYLLOTOXIN 1975

D Chemicals and Drugs
D02.455 Hydrocarbons 139
D02.455.426 Hydrocarbons, Cyclic 24
D02.455.426.559 Hydrocarbons, Aromatic 50
D02.455.426.559.389 Benzene Derivatives 73
D02.455.426.559.389.140 Benzyl Compounds 74
D02.455.426.559.389.140.450 Lignans 63
D02.455.426.559.389.140.450.388 Flavonolignans 22
D02.455.426.559.389.140.450.582 Masoprocol 7
D02.455.426.559.389.140.450.777 Podophyllotoxin 18
D02.455.426.559.847 Polycyclic Aromatic Hydrocarbons 468
D02.455.426.559.847.638 Naphthalenes 187
D02.455.426.559.847.638.960 Tetrahydronaphthalenes 26
D02.455.426.559.847.638.960.400 8-Hydroxy-2-(di-n-propylamino)tetralin 4
D02.455.426.559.847.638.960.423 Bexarotene 11
D02.455.426.559.847.638.960.446 Bunolol
D02.455.426.559.847.638.960.585 Mibefradil 9
D02.455.426.559.847.638.960.675 Podophyllotoxin 18
D02.455.426.559.847.638.960.675.250 Etoposide 189
D02.455.426.559.847.638.960.837 Tetralones
D04.615.638 Naphthalenes 187
D04.615.638.960 Tetrahydronaphthalenes 26
D04.615.638.960.423 Bexarotene 11
D04.615.638.960.446 Bunolol
D04.615.638.960.585 Mibefradil 9
D04.615.638.960.675 Podophyllotoxin 18
D04.615.638.960.675.250 Etoposide 189
D04.615.638.960.837 Tetralones

GP 11 Chemical MeSH Browser

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