Prostaglandins E [prostaglandiny E]
- Terms
-
PGE
(11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.
- Annotation
- /chem syn permitted: do not convert to PROSTAGLANDINS E, SYNTHETIC
- DUI
- D011458 MeSH Browser
- CUI
- M0017810
- Previous indexing
- Prostaglandins (1966-1974)
- History note
- 75
- Public note
- 75
Combination
- analogs & derivatives
- Prostaglandins E, Synthetic
Allowable subheadings
- AD
- administration & dosage 41
- AE
- adverse effects 10
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors 3
- BI
- biosynthesis 1
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism 3
- PK
- pharmacokinetics 2
- PD
- pharmacology 23
- PH
- physiology 8
- PO
- poisoning 1
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 59
- TO
- toxicity
- UR
- urine
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