Epoprostenol [epoprostenol]
- Terms
-
epoprostenol sodný
Flolan
PGI2
PGX
prostacyklin
prostaglandin I2
sodná sůl epoprostenolu
-
Epoprostanol
Epoprostenol Sodium
Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer
Flolan
Prostacyclin
Prostaglandin I(2)
Prostaglandin I2
Veletri
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
- DUI
- D011464 MeSH Browser
- CUI
- M0017816
- CAS
- Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (5Z,9alpha,11alpha,13E,15S)-
- Previous indexing
- Prostaglandins (1966-1977)
- History note
- 1991 (1978); use PROSTAGLANDINS X 1978-1990; for PROSTACYCLIN use PROSTACYCLINS 1978-1993; for PROSTAGLANDIN I2 use PROSTAGLANDINS I2 1982-1993; for PROSTAGLANDIN X use PROSTAGLANDINS X 1991-1993
- Public note
- 1991; see PROSTAGLANDINS X 1978-1990; for PROSTACYCLIN see PROSTACYCLINS 1978-1993; for PROSTAGLANDIN I2 see PROSTAGLANDINS I2 1982-1993; for PROSTAGLANDIN X see PROSTAGLANDINS X 1991-1993
Allowable subheadings
- AD
- administration & dosage 23
- AE
- adverse effects 7
- AG
- agonists 0
- AA
- analogs & derivatives 23
- AN
- analysis 0
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 1
- BL
- blood 1
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 1
- EC
- economics 1
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 3
- PK
- pharmacokinetics 5
- PD
- pharmacology 19
- PH
- physiology 3
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 47
- TO
- toxicity 0
- UR
- urine 0