Epoprostenol [epoprostenol]

topical
85
Terms

epoprostenol sodný
Flolan
PGI2
PGX
prostacyklin
prostaglandin I2
sodná sůl epoprostenolu

 

Epoprostanol
Epoprostenol Sodium
Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer
Flolan
Prostacyclin
Prostaglandin I(2)
Prostaglandin I2
Veletri

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Definition

A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).

DUI
D011464 MeSH Browser
CUI
M0017816
CAS
Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (5Z,9alpha,11alpha,13E,15S)-
Previous indexing
Prostaglandins (1966-1977)
History note
1991 (1978); use PROSTAGLANDINS X 1978-1990; for PROSTACYCLIN use PROSTACYCLINS 1978-1993; for PROSTAGLANDIN I2 use PROSTAGLANDINS I2 1982-1993; for PROSTAGLANDIN X use PROSTAGLANDINS X 1991-1993
Public note
1991; see PROSTAGLANDINS X 1978-1990; for PROSTACYCLIN see PROSTACYCLINS 1978-1993; for PROSTAGLANDIN I2 see PROSTAGLANDINS I2 1982-1993; for PROSTAGLANDIN X see PROSTAGLANDINS X 1991-1993

D Chemicals and Drugs
D10 Lipids 2 524
D10.251 Fatty Acids 1 428
D10.251.355.255 Eicosanoids 96
D10.251.355.255.550 Prostaglandins 663
D10.251.355.255.550.550 Prostaglandins I 5
D10.251.355.255.550.550.500 Epoprostenol 85
D23.469.050 Autacoids 3
D23.469.050.175 Eicosanoids 96
D23.469.050.175.725 Prostaglandins 663
D23.469.050.175.725.550 Prostaglandins I 5
D23.469.050.175.725.550.500 Epoprostenol 85