Secretory Component [sekreční komponenta]
- Terms
-
Secretory Piece
The extracellular moiety of the POLYMERIC IMMUNOGLOBULIN RECEPTOR found alone or complexed with IGA or IGM, in a variety of external secretions (tears, bile, colostrum.) Secretory component is derived by proteolytic cleavage of the receptor during transcytosis. When immunoglobulins IgA and IgM are bound to the receptor, during their transcytosis secretory component becomes covalently attached to them generating SECRETORY IMMUNOGLOBULIN A or secretory IMMUNOGLOBULIN M.
- DUI
- D012635 MeSH Browser
- CUI
- M0019591
- Previous indexing
- Colostrum (1973-1975); IgA (1973-1975); Immunoglobulin Fragments (1973-1975)
- History note
- 91(76); was see under IMMUNOGLOBULIN FRAGMENTS 1976-90
- Public note
- 91; was see under IMMUNOGLOBULIN FRAGMENTS 1976-90
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 1
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CH
- chemistry 0
- CL
- classification 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 1
- IP
- isolation & purification 0
- ME
- metabolism 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0