A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.

DUI

D013407 MeSH Browser

CUI

M0020733

CAS

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2S-cis)-

Previous indexing

Enzyme Inhibitors (1975-1987); Beta Lactamases/antagonists & inhibitors (1979-1987); Enzymes/antagonists & inhibitors (1966-1974); Penicillanic Acids (1971-1987)

History note

88

Public note

88