Thienamycins [thienamyciny]
- Terms
-
thienamycinová antibiotika
thienamycinová třída antibiotik
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Antibiotics, Thienamycin
Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.
- DUI
- D013845 MeSH Browser
- CUI
- M0021334
- Previous indexing
- Antibiotics (1966-1982); Amides (1966-1973); Lactams (1974-1982)
- History note
- 83
- Public note
- 83
Allowable subheadings
- AD
- administration & dosage 9
- AE
- adverse effects 4
- AG
- agonists 0
- AN
- analysis 1
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 1
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 1
- IP
- isolation & purification 0
- ME
- metabolism 3
- PK
- pharmacokinetics 5
- PD
- pharmacology 16
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 14
- TO
- toxicity 0
- UR
- urine 0