The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.

Annotation

coordinate with recipient/genet if permitted + specific donor/genet; do not confuse with genetic transvection, an epigenetic phenomenon (index under EPIGENESIS, GENETIC)

DUI

D014162 MeSH Browser

CUI

M0021796

Previous indexing

Transformation, Genetic (1968-1974)

History note

78(75); was see under TRANSFORMATION, GENETIC 1975-77

Public note

78; was see under TRANSFORMATION, GENETIC 1975-77