2',5'-Oligoadenylate Synthetase [2',5'-oligoadenylátsynthetasa]

topical
6
Terms

2-5A syntetáza
2',5'-oligoadenylát syntetáza

 

(2'-5')An Polymerase
2-5A Synthetase
2,5 Oligoadenylate Polymerase
2,5 Oligoadenylate Synthetase
2',5'-Oligo(A) Polymerase
2',5'-Oligo(A) Synthetase
2',5'-Oligoadenylate Polymerase
ATP-(2'-5')oligo(A)adenylyltransferase

Persistent link   https://www.medvik.cz/link/D015088
Definition

An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions.

DUI
D015088 MeSH Browser
CUI
M0023207
Previous indexing
Nucleotidyltransferases (1966-1982)
History note
83
Public note
83

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood 1
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 4
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 2
PK
pharmacokinetics
PD
pharmacology
PH
physiology 1
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D01 Inorganic Chemicals 68
D02 Organic Chemicals 391
D03 Heterocyclic Compounds 190
D04 Polycyclic Compounds 65
D05 Macromolecular Substances 103
D06 Hormones, Hormone Substitutes, and Hormone Antagonists 43
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 549
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.445 Nucleotidyltransferases 15
D08.811.913.696.445.018 mRNA Guanylyltransferases
D08.811.913.696.445.035 N-Acylneuraminate Cytidylyltransferase
D08.811.913.696.445.184 Choline-Phosphate Cytidylyltransferase
D08.811.913.696.445.308 DNA Nucleotidyltransferases 6
D08.811.913.696.445.400 Glucose-1-Phosphate Adenylyltransferase
D08.811.913.696.445.600 Nicotinamide-Nucleotide Adenylyltransferase 3
D08.811.913.696.445.625 2',5'-Oligoadenylate Synthetase 6
D08.811.913.696.445.650 Polynucleotide Adenylyltransferase 3
D08.811.913.696.445.692 Rec A Recombinases 13
D08.811.913.696.445.735 RNA Nucleotidyltransferases 6
D08.811.913.696.445.800 Sulfate Adenylyltransferase 2
D08.811.913.696.445.825 Transposases 11
D08.811.913.696.445.837 Transposon Resolvases 1
D08.811.913.696.445.850 UDPglucose-Hexose-1-Phosphate Uridylyltransferase 1
D08.811.913.696.445.875 UTP-Glucose-1-Phosphate Uridylyltransferase
D08.811.913.696.445.900 UTP-Hexose-1-Phosphate Uridylyltransferase 6
D08.811.913.696.445.950 VDJ Recombinases 1
D09 Carbohydrates 723
D10 Lipids 2 526
D12 Amino Acids, Peptides, and Proteins 16
D13 Nucleic Acids, Nucleotides, and Nucleosides 9
D20 Complex Mixtures 19
D23 Biological Factors 143
D25 Biomedical and Dental Materials 110
D26 Pharmaceutical Preparations 7 041
D27 Chemical Actions and Uses 374

OAS1 protein, human Chemical MeSH Browser

OAS2 protein, human Chemical MeSH Browser

OAS3 protein, human Chemical MeSH Browser

OASL protein, human Chemical MeSH Browser

Oas1b protein, mouse Chemical MeSH Browser

Oas1c protein, mouse Chemical MeSH Browser

Oas1d protein, mouse Chemical MeSH Browser

Oas1g protein, mouse Chemical MeSH Browser

Oasl1 protein, mouse Chemical MeSH Browser

Oasl2 protein, mouse Chemical MeSH Browser

p30 oligoadenylate synthetase Chemical MeSH Browser

p56 oligoadenylate synthetase Chemical MeSH Browser

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