4-Nitroquinoline-1-oxide [4-nitrochinolin-1-oxid]

topical
8
Terms

4-Nitroquinoline-N-oxide

Persistent link   https://www.medvik.cz/link/D015112
Definition

A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage.

DUI
D015112 MeSH Browser
CUI
M0023243
CAS
Quinoline, 4-nitro-, 1-oxide
Previous indexing
Nitro Compounds (1972-1974); Quinolines (1970-1974); Cyclic N-Oxides (1972-1974)
History note
91(75); was see under NITROQUINOLINES 1975-90
Public note
91; was see under NITROQUINOLINES 1975-90

Allowable subheadings

AD
administration & dosage 1
AE
adverse effects
AA
analogs & derivatives
AN
analysis
CS
chemical synthesis
CH
chemistry 1
CL
classification
EC
economics
HI
history
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology 1
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity 6

D Chemicals and Drugs
D02 Organic Chemicals 391
D02.640 Nitro Compounds 89
D02.640.820 Nitroquinolines 3
D02.640.820.600 4-Nitroquinoline-1-oxide 8
D03 Heterocyclic Compounds 190
D03.633 Heterocyclic Compounds, Fused-Ring
D03.633.100 Heterocyclic Compounds, 2-Ring 24
D03.633.100.810 Quinolines 262
D03.633.100.810.470 Nitroquinolines 3
D03.633.100.810.470.450 4-Nitroquinoline-1-oxide 8
D03.633.100.810.470.600 Oxamniquine 4
D03.661 Heterocyclic Oxides
D03.661.243 Cyclic N-Oxides 35
D03.661.243.320 4-Hydroxyaminoquinoline-1-oxide
D03.661.243.500 4-Nitroquinoline-1-oxide 8
D03.661.243.930 Triacetoneamine-N-Oxyl

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