HLA-B Antigens [HLA-B antigeny]
- Terms
-
Antigens, HLA-B
HLA-B
HLA-B Antigen
Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.
- Annotation
- general; prefer specifics
- DUI
- D015235 MeSH Browser
- CUI
- M0023414
- Previous indexing
- HLA Antigens (1975-1988); Histocompatibility Antigens (1975-1981)
- History note
- 89
- Public note
- 89
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 2
- AN
- analysis 7
- BI
- biosynthesis 0
- BL
- blood 2
- CF
- cerebrospinal fluid 0
- CH
- chemistry 0
- CL
- classification 1
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 15
- HI
- history 0
- IM
- immunology 11
- IP
- isolation & purification 1
- ME
- metabolism 2
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0