Fibrinogens, Abnormal [fibrinogeny abnormální]
topical
20
- Terms
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Abnormal Fibrinogens
Persistent link
https://www.medvik.cz/link/D015241
Definition
Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilized fibrin, such as cleavage of the fibrinopeptides by thrombin, polymerization and cross-linking of fibrin. The resulting dysfibrinogenemias can be clinically silent or can be associated with bleeding, thrombosis or defective wound healing.
- DUI
- D015241 MeSH Browser
- CUI
- M0023429
- Previous indexing
- Fibrinogen (1966-1988)
- History note
- 89
- Public note
- 89
Allowable subheadings
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- analysis 3
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- CF
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- CH
- chemistry 1
- CL
- classification 0
- DF
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- DE
- drug effects 0
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- GE
- genetics 12
- HI
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- IM
- immunology 1
- IP
- isolation & purification 1
- ME
- metabolism 4
- PK
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- PH
- physiology 1
- PO
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- RE
- radiation effects 0
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- SD
- supply & distribution 0
- TU
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- TO
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- ultrastructure 1
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Occurrences in Medvik records
D
Chemicals and Drugs