Thiorphan [thiorfan]
topical
8
- Terms
-
(3-Mercapto-2-benzylpropionyl)glycine
Thiorphan, (R)-Isomer
Thiorphan, (S)-Isomer
Tiorphan
Persistent link
https://www.medvik.cz/link/D015244
Definition
A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
- DUI
- D015244 MeSH Browser
- CUI
- M0023434
- CAS
- Glycine, N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-, (+-)-
- Previous indexing
- Mercaptopropionylglycine/analogs & derivatives (1980-1988)
- History note
- 89
- Public note
- 89
Allowable subheadings
- AD
- administration & dosage 2
- AE
- adverse effects 1
- AG
- agonists
- AA
- analogs & derivatives 8
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics 2
- PD
- pharmacology 3
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 6
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D02.886.030.215
Cysteic Acid
D12.125.166.215
Cysteic Acid
D12.125.481.700
N-substituted Glycines