DNA Modification Methylases [DNA modifikační methylasy]
- Terms
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DNA modifikační metylázy
modifikační metylázy
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DNA Modification Methyltransferases
Modification Methylases
Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the host-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognized by the restriction endonucleases of similar specificity and destroyed by cleavage. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms.
- DUI
- D015254 MeSH Browser
- CUI
- M0023492
- Previous indexing
- Methyltransferases (1971-1988); DNA (Cytosine-5-)-Methyltransferase (1975-1988)
- History note
- 1989
- Public note
- 1989
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis 1
- AI
- antagonists & inhibitors 2
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 16
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 4
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
AloI restriction-modification enzyme Chemical MeSH Browser
DNA methyltransferase M.BstC8I, Bacillus stearothermophilus Chemical MeSH Browser
DNA modification methylase CfrBI Chemical MeSH Browser
DNA modification methylase DcmII Chemical MeSH Browser
DNA modification methylase HgiDII Chemical MeSH Browser
DNA modification methylase SphI, Streptomyces Chemical MeSH Browser
DNA modification methylase XorII, Xanthomonas oryzae Chemical MeSH Browser
Dnmt3a1 protein, mouse Chemical MeSH Browser
HP1352 protein, Helicobacter pylori Chemical MeSH Browser
METTL21A protein, human Chemical MeSH Browser
MGMT protein, human Chemical MeSH Browser
MGMT protein, mouse Chemical MeSH Browser
Mgmt protein, rat Chemical MeSH Browser
Ppu21IM methyltransferase, Pseudomonas Chemical MeSH Browser
ZMET2 protein, Zea mays Chemical MeSH Browser