1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine [1-methyl-4-fenyl-1,2,3,6-tetrahydropyridin]

topical
4
Terms

MPTP
N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Persistent link   https://www.medvik.cz/link/D015632
Definition

A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.

DUI
D015632 MeSH Browser
CUI
M0023971
CAS
Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl-
Previous indexing
Pyridines (1966-1989)
History note
90
Public note
90

Combination

poisoning
MPTP Poisoning
toxicity
MPTP Poisoning

Allowable subheadings

AD
administration & dosage 1
AE
adverse effects 1
AG
agonists
AA
analogs & derivatives 1
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PK
pharmacokinetics
PD
pharmacology 1
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 1
UR
urine

D Chemicals and Drugs
D01 Inorganic Chemicals 68
D02 Organic Chemicals 391
D03 Heterocyclic Compounds 190
D03.383 Heterocyclic Compounds, 1-Ring 34
D03.383.725 Pyridines 1 086
D03.383.725.024 2-Pyridinylmethylsulfinylbenzimidazoles 23
D03.383.725.050 Aminopyridines 120
D03.383.725.068 Atazanavir Sulfate 5
D03.383.725.086 Betahistine 24
D03.383.725.150 Carbolines 143
D03.383.725.180 Clopidol 2
D03.383.725.192 Dabigatran 308
D03.383.725.203 Dihydropyridines 112
D03.383.725.210 Dimethindene 13
D03.383.725.220 2,2'-Dipyridyl 16
D03.383.725.227 Disopyramide 8
D03.383.725.259 Doxylamine 2
D03.383.725.322 Eszopiclone 1
D03.383.725.354 Etoricoxib 2
D03.383.725.385 Indinavir 6
D03.383.725.394 Isonicotinic Acids 42
D03.383.725.450 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 4
D03.383.725.463 Metyrapone 30
D03.383.725.495 Naphthylvinylpyridine
D03.383.725.506 Nevirapine 6
D03.383.725.518 Nicotine 400
D03.383.725.547 Nicotinic Acids 98
D03.383.725.565 Nicotinyl Alcohol
D03.383.725.620 Pheniramine 6
D03.383.725.676 Picolines 12
D03.383.725.705 Picolinic Acids 10
D03.383.725.740 Polyvinylpyridine N-Oxide 8
D03.383.725.762 Pyridinium Compounds 219
D03.383.725.791 Pyridones 300
D03.383.725.812 Pyrithioxin 24
D03.383.725.822 Quinolinic Acids 7
D03.383.725.836 Risedronic Acid 9
D03.383.725.849 Thienopyridines 12
D03.383.725.877 Tolperisone 12
D03.383.725.905 Torsemide 1
D03.383.725.932 Triprolidine
D03.383.725.942 Tropicamide 4
D03.383.725.971 Zolpidem 26
D04 Polycyclic Compounds 65
D05 Macromolecular Substances 103
D06 Hormones, Hormone Substitutes, and Hormone Antagonists 43
D08 Enzymes and Coenzymes 7
D09 Carbohydrates 723
D10 Lipids 2 526
D12 Amino Acids, Peptides, and Proteins 16
D13 Nucleic Acids, Nucleotides, and Nucleosides 9
D20 Complex Mixtures 19
D23 Biological Factors 143
D25 Biomedical and Dental Materials 110
D26 Pharmaceutical Preparations 7 041
D27 Chemical Actions and Uses 374

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