1-Methyl-4-phenylpyridinium [1-methyl-4-fenylpyridinium]
topical
1
- Terms
-
chlorid MPP+
Cyperquat
MPP+
-
1-Methyl-4-phenylpyridine
1-Methyl-4-phenylpyridinium Chloride
1-Methyl-4-phenylpyridinium Ion
Cyperquat
N-Methyl-4-phenylpyridine
N-Methyl-4-phenylpyridinium
Persistent link
https://www.medvik.cz/link/D015655
Definition
An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.
- DUI
- D015655 MeSH Browser
- CUI
- M0023993
- CAS
- Pyridinium, 1-methyl-4-phenyl-
- Previous indexing
- Pyridinium Compounds (1968-1989)
- History note
- 90
- Public note
- 90
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