Giant Cells, Langhans [Langhansovy obrovské buňky]
- Terms
-
Langhans Giant Cells
Langhans-Type Giant Cells
Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity.
- Annotation
- do not confuse with LANGERHANS CELLS nor with ISLETS OF LANGERHANS
- DUI
- D015744 MeSH Browser
- CUI
- M0024133
- Previous indexing
- Macrophages (1966-1989); Granuloma, Giant Cell (1977-1989)
- History note
- 91(90); was see under GIANT CELLS 1990
- Public note
- 91; was see under GIANT CELLS 1990
Allowable subheadings
- CH
- chemistry
- CL
- classification
- CY
- cytology 1
- DE
- drug effects
- EN
- enzymology
- IM
- immunology
- ME
- metabolism
- MI
- microbiology
- PS
- parasitology
- PA
- pathology
- PH
- physiology 1
- RE
- radiation effects
- TR
- transplantation
- UL
- ultrastructure
- VI
- virology