Obrovské vícejaderné buňky charakteristické pro některé záněty s tvorbou granulomů. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )

Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity.

Anotace

do not confuse with LANGERHANS CELLS nor with ISLETS OF LANGERHANS

DUI

D015744 MeSH Prohlížeč

CUI

M0024133

Předchozí užití

Macrophages (1966-1989); Granuloma, Giant Cell (1977-1989)

Historická pozn.

91(90); was see under GIANT CELLS 1990

Veřejná pozn.

91; was see under GIANT CELLS 1990