2-Amino-5-phosphonovalerate [2-amino-5-fosfonovalerát]
topical
8
- Terms
-
AP-5
AP5
APV
D-2-amino-5-fosfonovalerát
D-APV
DL-APV
α-amino-5-fosfonovalerát
-
2-Amino-5-phosphonopentanoate
2-Amino-5-phosphonopentanoic Acid
2-Amino-5-phosphonovaleric Acid
2-APV
5-Phosphononorvaline
d-APV
dl-APV
Persistent link
https://www.medvik.cz/link/D015763
Definition
The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
- DUI
- D015763 MeSH Browser
- CUI
- M0024150
- CAS
- Norvaline, 5-phosphono-
- Previous indexing
- Anticonvulsants (1966-1989); Valine (1966-1974); Valine/analogs & derivatives (1975-1989)
- History note
- 90
- Public note
- 90
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives 6
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 5
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs