Trichosanthin [trichosanthin]
- Terms
-
alpha-Trichosanthin
Compound Q
GLQ-223
GLQ223
T'ien-hua-fen
Tian-hua-fen
Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.
- Annotation
- /drug eff /ultrastruct permitted
- DUI
- D015978 MeSH Browser
- CUI
- M0024413
- CAS
- Proteins, specific or class, trichosanthins
- Previous indexing
- Abortifacient Agents, Non-Steroidal (1977-1989); Plant Proteins (1976-1989)
- History note
- 90
- Public note
- 90
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
beta-trichosanthin Chemical MeSH Browser
bromodextran-trichosanthin Chemical MeSH Browser