Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).

Annotation

coordinate with disease /radiother

DUI

D016499 MeSH Browser

CUI

M0025194

Previous indexing

Antibodies, Monoclonal/therapeutic use (1984-1991); Immunotherapy (1984-1991); specific radioisotope/therapeutic use (1981-1991)

History note

92

Public note

92