Clarithromycin [klarithromycin]
- Terms
-
clarithromycin
klaritromycin
-
6-O-Methylerythromycin
A-56268
Biaxin
TE-031
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
- DUI
- D017291 MeSH Browser
- CUI
- M0026249
- CAS
- Erythromycin, 6-O-methyl-
- Previous indexing
- Erythromycin/analogs & derivatives (1987-1992)
- History note
- 93; was CLARITHROMYCIN (NM) 1987-92
- Online note
- use CLARITHROMYCIN (NM) to search CLARITHROMYCIN 1987-92
- Public note
- 93; CLARITHROMYCIN was indexed under ERYTHROMYCIN/analogs & derivatives 1987-92
Allowable subheadings
- AD
- administration & dosage 50
- AE
- adverse effects 8
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 2
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 3
- PK
- pharmacokinetics 8
- PD
- pharmacology 28
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 67
- TO
- toxicity
- UR
- urine