A malignancy arising in uterine cervical epithelium and confined thereto, representing a continuum of histological changes ranging from well-differentiated CIN 1 (formerly, mild dysplasia) to severe dysplasia/carcinoma in situ, CIN 3. The lesion arises at the squamocolumnar cell junction at the transformation zone of the endocervical canal, with a variable tendency to develop invasive epidermoid carcinoma, a tendency that is enhanced by concomitant human papillomaviral infection. (Segen, Dictionary of Modern Medicine, 1992)

Annotation

coordinate with UTERINE CERVICAL NEOPLASMS

DUI

D018290

CUI

M0027524

Last active year

2022

Previous indexing

Carcinoma, Squamous Cell (1966-1993); Carcinoma in Situ (1973-1993); Cervix Dysplasia (1977-1993); Cervix Neoplasms (1966-1993)

History note

94

Public note

94