Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)

Annotation

IM general only; when pertinent add CLINICAL TRIAL (PT) or RANDOMIZED CONTROLLED TRIAL (PT)

DUI

D018592 MeSH Browser

CUI

M0027868

History note

95

Public note

95