Interleukin-12 [interleukin-12]
- Terms
-
IL-12
-
Cytotoxic Lymphocyte Maturation Factor
Edodekin Alfa
IL 12
IL-12
IL-12 p70
IL12
Interleukin 12
Interleukin-12 p70
Natural Killer Cell Stimulatory Factor
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.
- DUI
- D018664 MeSH Browser
- CUI
- M0027969
- Previous indexing
- Interleukins (1991-1994)
- History note
- 1995 (1991)
- Public note
- 1995; INTERLEUKIN 12 was indexed under INTERLEUKINS 1991-1994; INTERLEUKIN-12 P70 was indexed under INTERLEUKIN-12 2003-2006
Allowable subheadings
- AD
- administration & dosage 5
- AE
- adverse effects 4
- AG
- agonists
- AN
- analysis 1
- AI
- antagonists & inhibitors 18
- BI
- biosynthesis 7
- BL
- blood 5
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 4
- CL
- classification
- DF
- deficiency 1
- EC
- economics
- GE
- genetics 7
- HI
- history
- IM
- immunology 22
- IP
- isolation & purification
- ME
- metabolism 4
- PK
- pharmacokinetics
- PD
- pharmacology 7
- PH
- physiology 6
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 18
- TO
- toxicity
- UR
- urine
99mTc-HYNIC-interleukin-12 Chemical MeSH Browser
Flexi-12 protein, human Chemical MeSH Browser
GEN-1 Chemical MeSH Browser
IL-12 p80, mouse Chemical MeSH Browser
NHS-IL12 immunocytokine Chemical MeSH Browser