Genes, erbB-2 [geny erbB-2]
topical
219
- Terms
-
gen c-erbB-2
geny erbB2
geny HER2
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c-erbB-2 Genes
c-erbB-2 Proto-Oncogenes
erbB-2 Genes
Genes, erbb2
Genes, HER-2
Genes, HER2
Genes, neu
Persistent link
https://www.medvik.cz/link/D018734
Definition
The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.
- Annotation
- in titles & translations spell as erbB-2; GENES, ERBB-1 is also available
- DUI
- D018734 MeSH Browser
- CUI
- M0028066
- Previous indexing
- Oncogenes (1986-1994); Proto-Oncogenes (1986-1994)
- History note
- 1995
- Public note
- 1995
Allowable subheadings
- DE
- drug effects 88
- ES
- ethics 0
- GE
- genetics 70
- IM
- immunology 22
- PH
- physiology 3
- RE
- radiation effects 1
...
Occurrences in Medvik records
G
Phenomena and Processes