Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization [spektrometrie hmotnostní - ionizace laserem za účasti matrice]
- Terms
-
MALDI-TOF MS
matrix assisted laser desorption/ionization
Matrix Assisted Laser Desorption/Ionization, Time of Flight
SELDI-TOF-MS
spektrometrie hmotnostní MALDI
-
Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted
MALD-MS
MALDI
MALDI-MS
Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization
Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
MS-MALD
SELDI-TOF-MS
Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization
Surface Enhanced Laser Desorption Ionization Mass Spectrometry
A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
- DUI
- D019032 MeSH Browser
- CUI
- M0028408
- Previous indexing
- Spectrum Analysis, Mass (1989-1995)
- History note
- 96
- Public note
- 96
Allowable subheadings
- CL
- classification 0
- EC
- economics 0
- ES
- ethics 0
- HI
- history 1
- IS
- instrumentation 20
- MT
- methods 185
- ST
- standards 5
- SN
- statistics & numerical data 7
- TD
- trends 1
- VE
- veterinary 4