A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)

DUI

D019269 MeSH Browser

CUI

M0028698

Previous indexing

Phosphatidylinositol Phosphates (1994-1996); Phosphatidylinositols (1981-1993)

History note

97; see PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE (NM) 1981-96

Online note

use PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE (NM) to search PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE 1981-96

Public note

97; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE was indexed under PHOSPHATIDYLINOSITOL PHOSPHATES 1994-96 & PHOSPHOINOSITIDES 1981-93